PDZ15B,115

PDZ15B,115 likely refers to a PDZ domain labeled as 15B (in a given protein or dataset) and may include a residue range or entry tag (115). Here is a concise introduction to PDZ domains in general, which covers the likely context.
- What is a PDZ domain? A modular protein interaction domain (~80–90 aa) found in scaffolding proteins such as PSD-95, SAP, Dlg, and ZO-1. It folds as a beta-sandwich with an N-terminal and a C-terminal binding groove that recognizes short C-terminal peptide motifs of partner proteins.
- Binding motifs (classical): Class I (S/T-X-Φ-COOH), Class II (Φ-X-Φ-COOH), Class III (D/E-X-Φ-COOH), where Φ is a hydrophobic residue. The GLGF loop is a hallmark that helps form the peptide-binding pocket.
- Roles: Assemble signaling complexes at membranes (e.g., synapses, tight junctions); can function as scaffolds, determine subcellular localization, and regulate signaling through post-translational modifications or alternative splicing.
- If you can share the specific protein name, UniProt ID, or organism for PDZ15B,115, I can tailor a focused intro with structure, partners, and relevance.

I don’t recognize PDZ15B,115 unambiguously—can you give the manufacturer or a photo? If it’s a 15 V Zener, common equivalents by power/package are: BZX84C15 (SMD, ~0.5 W), BZT52H‑B15 (SOD‑123, ~0.5–1 W), or 1N4744A (through‑hole, 1 W). Choose by power dissipation, package and tolerance—send more details for an exact match.

Assuming PDZ15B and PDZ115 refer to PDZ-domain containing proteins/domains, common application areas include:
- Research tools for mapping protein–protein interactions and signaling networks (PPI assays, pull-downs, colocalization)
- Drug discovery: designing inhibitors/peptidomimetics to block PDZ-mediated interactions
- Neuroscience: studying synaptic receptor clustering, trafficking, plasticity, learning and memory
- Disease research: cancer and cardiovascular signaling where PDZ interactions regulate receptor trafficking and pathways
- Diagnostics/biomarkers: PDZ-interaction signatures as disease indicators
- Synthetic biology: engineered PDZ scaffolds for modular signaling and biosensors

I don’t have enough info to be certain — PDZ15B,115 can refer to different manufacturers’ 15 V Zener parts. Please provide the manufacturer or a datasheet/link (or the full ordering code) and I’ll tell you the exact package type.